Cytotoxic xanthones isolated from Calophyllum depressinervosum and Calophyllum buxifolium with antioxidant and cytotoxic activities
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منابع مشابه
Cytotoxic prenylated xanthones from Calophyllum inophyllum.
A new prenylated xanthone (1), named caloxanthone N, together with two known constituents, gerontoxanthone C (2) and 2-hydroxyxanthone (3), was isolated from the ethanolic extract of the twigs of Calophyllum inophyllum. Their structures were completely elucidated using a combination of 1D, 2D NMR techniques (COSY, HMQC, HMBC, and ROESY) and HR-ESI-MS analyses. Compounds 1 and 2 exhibited cytoto...
متن کاملIn vitro antioxidant, cholinesterase and tyrosinase inhibitory activities of Calophyllum symingtonianum and Calophyllum depressinervosum (Guttiferae)
Currently, there is global attention focused on finding antioxidants from natural sources, due to common synthetic antioxidants such as butylated hydroxyanisole and butylated hydroxytoluene (BHT) being reported to cause adverse effects including enzymatic and lipid alterations[1]. Antioxidants protect the body from free radicals and reactive oxygen species (ROS). ROS activity leads to skin agei...
متن کاملAntimicrobial, Antioxidant, Anti-Inflammatory and Cytotoxic Activities of Garcinia Eugenifolia and Calophyllum Enervosum
Chemical investigation of Garcinia eugenifolia and Calophyllum enervosum yielded six compounds. One of these was found to be a novel compound identified as enervosanone. Five known compounds cambogin, epicatechin, osajaxanthone, rubraxanthone and isocowanol, were also isolated. These compounds were tested for their bioactivity as antimicrobial, antioxidant and cytotoxicagents. Antimicrobial...
متن کاملTwo new xanthones from Calophyllum nodusum (Guttiferae).
The air-dried powdered stem bark of Calophyllum nodusum (Guttiferea) collected from Sandakan (Sabah, Malaysia), was extracted sequentially with hexane, chloroform and methanol. The solvents were removed by rotary evaporator to give dark viscous extracts. Detailed and repeated chromatographic separation of the extracts lead to isolation of two new xanthones, identified as nodusuxanthone and trap...
متن کاملantimicrobial, antioxidant, anti-inflammatory and cytotoxic activities of garcinia eugenifolia and calophyllum enervosum
chemical investigation of garcinia eugenifolia and calophyllum enervosum yielded six compounds. one of these was found to be a novel compound identified as enervosanone. five known compounds cambogin, epicatechin, osajaxanthone, rubraxanthone and isocowanol, were also isolated. these compounds were tested for their bioactivity as antimicrobial, antioxidant and cytotoxicagents. antimicrobial ass...
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ژورنال
عنوان ژورنال: Food and Chemical Toxicology
سال: 2019
ISSN: 0278-6915
DOI: 10.1016/j.fct.2019.110800